Pennsylvania Neighborhoods S
- Salem Square (5)
- Scott Township (4)
- Shade Gap (2)
- Shadyside (59)
- Sheraden (5)
- Shiloh (4)
- Sinking Spring (3)
- Slatington Historic District (4)
- Snowball Gate (1)
- Society Hill (20)
- South Ardmore (3)
- South Duquesne Heights (1)
- South Easton (5)
- South Harrisburg (2)
- South Philadelphia East (19)
- South Philadelphia West (63)
- South Shore (2)
- South Side (34)
- South Suburban Erie (5)
- Southeast Community (3)
- Southeast Erie (6)
- Southeast Reading (4)
- Southside (6)
- Southside Flats (95)
- Southside Slopes (25)
- Southside-Lehigh (35)
- Southwest Center City (57)
- Southwest Reading (4)
- Southwest York (7)
- Spring Hill City View (4)
- Springetts Manor-Yorklyn (3)
- Spruce Hill (86)
- Spry (3)
- Squirrel Hill North (37)
- Squirrel Hill South (61)
- St Mary's (5)
- Stadium District (4)
- Stanton Heights (9)
- State College South (2)
- Stevens (2)
- Stonybrook (1)
- Stonybrook-Wilshire (2)
- Strasburg/Paradise/Gap (1)
- Strip District (13)
- Sun Hill (1)
- Sun Village (7)
- Swarthmore (3)
- Swisshelm Park (1)