Pennsylvania Neighborhoods S
- Salem Square (1)
- Scott Township (5)
- Shade Gap (2)
- Shadyside (34)
- Sheraden (2)
- Shiloh (5)
- Sinking Spring (4)
- Sixth Ward (1)
- Slatington Historic District (3)
- Society Hill (25)
- South Ardmore (7)
- South East Hills (1)
- South Easton (8)
- South Harrisburg (3)
- South Philadelphia East (29)
- South Philadelphia West (61)
- South Shore (2)
- South Side (38)
- South Suburban Erie (3)
- Southeast Community (4)
- Southeast Erie (5)
- Southeast Reading (8)
- Southside (3)
- Southside Flats (51)
- Southside Slopes (7)
- Southside-Lehigh (28)
- Southwest Center City (49)
- Southwest Reading (3)
- Southwest York (5)
- Spring Hill City View (1)
- Springetts Manor-Yorklyn (3)
- Spruce Hill (86)
- Spry (4)
- Squirrel Hill North (17)
- Squirrel Hill South (29)
- St Mary (3)
- St Mary's (3)
- Stadium District (5)
- Stanton Heights (1)
- Stevens (3)
- Stonybrook (1)
- Stonybrook-Wilshire (1)
- Strasburg/Paradise/Gap (2)
- Strip District (13)
- Sun Hill (1)
- Sun Village (6)
- Swarthmore (3)