Pennsylvania Neighborhoods S
- Salem Square (2)
- Scott Township (8)
- Shade Gap (2)
- Shadyside (77)
- Sheraden (9)
- Shiloh (6)
- Sixth Ward (1)
- Slatington Historic District (5)
- Society Hill (23)
- South Ardmore (7)
- South Duquesne Heights (5)
- South East Hills (1)
- South Easton (8)
- South Harrisburg (1)
- South Philadelphia East (31)
- South Philadelphia West (64)
- South Shore (6)
- South Side (33)
- South Suburban Erie (2)
- Southeast Community (7)
- Southeast Erie (5)
- Southeast Reading (6)
- Southside (4)
- Southside Flats (124)
- Southside Slopes (33)
- Southside-Lehigh (24)
- Southwest Center City (52)
- Southwest Reading (4)
- Southwest York (8)
- Spring Hill City View (3)
- Springetts Manor-Yorklyn (3)
- Spruce Hill (118)
- Spry (2)
- Squirrel Hill North (36)
- Squirrel Hill South (87)
- St Mary's (5)
- Stadium District (5)
- Stanton Heights (8)
- State College South (1)
- Stevens (7)
- Stonybrook-Wilshire (2)
- Strip District (11)
- Summer Hill (1)
- Sun Hill (3)
- Sun Village (2)
- Swoyersville (1)